Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication Practical components for three-dimensional molecular nanofabrication must be simple to produce, stereopure, rigid, and adaptable. We report a family of DNA tetrahedra, less than 10 nanometers on a side, that can self-assemble in seconds with near-quantitative yield of one diastereomer. They can be connected by programmable DNA linkers. Their triangulated architecture confers structural stability; by compressing a DNA tetrahedron with an atomic force microscope, we have measured the axial compressibility of DNA and observed the buckling of the double helix under high loads.
Molecular Machinery from DNA: Synthetic Biology from the Bottom up
Programmable DNA Nanosystem for Molecular Interrogation an embedded Förster Resonance Energy Transfer (FRET) system, in which one cyanine 3 (cy3) molecule is positioned on the frame and one cyanine 5 (cy5) molecule is on the ring, reports the relative position of the ring under various conditions
Hybrid, multiplexed, functional DNA nanotechnology for bioanalysis
Reversible Reconfiguration of DNA Origami Nanochambers Monitored by Single-Molecule FRET
Universal computing by DNA origami robots in a living animal (see also DNA computing).
Controlled Release of Encapsulated Cargo from a DNA Icosahedron using a Chemical Trigger
DNA Scissors Device Used to Measure MutS Binding to DNA Mis-pairs
Nanomechanical DNA origami 'single-molecule beacons' directly imaged by atomic force microscopy
A DNA-fuelled molecular machine made of DNA
Construction of a 4 Zeptoliters Switchable 3D DNA Box Origami
Molecular Engineering of DNA: Molecular Beacons
See also Atomically precise manufacturing