DNA

cosmos 18th November 2016 at 4:13pm
Genetics Molecular biology Nucleic acid

Desoxyribonucleic acid

See DNA nanotechnology, MMathPhys oral presentation

https://en.wikipedia.org/wiki/DNA

Structure of DNA

Covalent structure of DNA

DNA complexes

Base pairing of Nucleobases via Hydrogen bonding

DNA double helix

Can model DNA as a ribbon, and can define it's torsion. Boundaries of ribbon are the backbone, and they form the same surface that you get by twisting a normal ribbon.

Can also coarse-grain more, and model it as a curve.

Packing of DNA in a cell. See here

How DNA unties its own knots - Numberphile, using Type II topoisomerase (see more here). Drugs that target type II topoisomerase are used as antibiotics, because this enzyme is necessary for the cell to replicate correctly in bacteria. This is because the fact that DNA is a helix, and it forms a loop in bacteria means that when DNA is unzipped by helicase, the two single strand loops are interlinked. Topoisomerase then cuts and stiches DNA in such a way as to unlink them. See DNA replication

Structure of DNA in the Cell nucleus

Chromatin

Processes of DNA

DNA replication

Gene expression

DNA repair

Chemistry of DNA

https://www.technologyreview.com/s/419590/quantum-entanglement-holds-dna-together-say-physicists/

Molecular genetics