Mechanistic target of rapamycin

guillefix 4th November 2016 at 2:43pm

https://en.wikipedia.org/wiki/Mechanistic_target_of_rapamycin

A Kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, autophagy, transcription.

It's signalling circuit has been studied, for instance as an example of GP map bias: Evolvability and robustness in a complex signalling circuit.